History of Missouri Tigers
Versus South Carolina Gamecocks
| 09/22/12 | 10 | 31 | | Lost | | | @ Columbia, SC |
| 10/26/13 | 27 | 24 | (ot) | Lost | | | @ Columbia, MO |
| 09/27/14 | 21 | 20 | | Won | | | @ Columbia, SC |
| 10/03/15 | 10 | 24 | | Won | | | @ Columbia, MO |
| 11/05/16 | 21 | 31 | | Lost | +4.5 L | 56 U | @ Columbia, SC |
| 09/09/17 | 31 | 13 | | Lost | -2.5 L | 71 U | @ Columbia, MO |
| 10/06/18 | 35 | 37 | | Lost | -1 L | 63 O | @ Columbia, SC |
| 09/21/19 | 14 | 34 | | Won | -9.5 W | 61 U | @ Columbia, MO |
| 11/21/20 | 17 | 10 | | Won | -5 W | 57 U | @ Columbia, SC |
| 11/13/21 | 28 | 31 | | Won | pk W | 56.5 O | @ Columbia, MO |
| 10/29/22 | 23 | 10 | | Won | +3.5 W | 45.5 U | @ Columbia, SC |
| 10/21/23 | 12 | 34 | | Won | -7.5 W | 57.5 U | @ Columbia, MO |
| 11/16/24 | 30 | 34 | | Lost | +10.5 W | 42.5 O | @ Columbia, SC |
| totals | | 7-6 | (6-3) | |