History of South Carolina Gamecocks
Versus Missouri Tigers
| 09/22/12 | 10 | 31 | | Won | | | @ Columbia, SC |
| 10/26/13 | 27 | 24 | (ot) | Won | | | @ Columbia, MO |
| 09/27/14 | 21 | 20 | | Lost | | | @ Columbia, SC |
| 10/03/15 | 10 | 24 | | Lost | | | @ Columbia, MO |
| 11/05/16 | 21 | 31 | | Won | -4.5 W | 56 U | @ Columbia, SC |
| 09/09/17 | 31 | 13 | | Won | +2.5 W | 71 U | @ Columbia, MO |
| 10/06/18 | 35 | 37 | | Won | +1 W | 63 O | @ Columbia, SC |
| 09/21/19 | 14 | 34 | | Lost | +9.5 L | 61 U | @ Columbia, MO |
| 11/21/20 | 17 | 10 | | Lost | +5 L | 57 U | @ Columbia, SC |
| 11/13/21 | 28 | 31 | | Lost | pk L | 56.5 O | @ Columbia, MO |
| 10/29/22 | 23 | 10 | | Lost | -3.5 L | 45.5 U | @ Columbia, SC |
| 10/21/23 | 12 | 34 | | Lost | +7.5 L | 57.5 U | @ Columbia, MO |
| 11/16/24 | 30 | 34 | | Won | -10.5 L | 42.5 O | @ Columbia, SC |
| totals | | 6-7 | (3-6) | |