| Date | Visitor | Home | |
|---|---|---|---|
| September 20th: | Penn State (-21 1/2) 57 | Louisville 21 | |
| Baylor 3 | Michigan (-26 1/2) 38 | ||
| Michigan State 23 | Notre Dame (-2 1/2) 7 | ||
| Tennessee 20 | Florida (-4 1/2) 33 | ||
| Nebraska 27 | Washington (-3 1/2) 14 | ||
| Arizona 20 | Ohio State (-17 1/2) 28 | ||
| Iowa (-26 1/2) 63 | Iowa State 20 | ||
| Oklahoma 36 | California (-4 1/2) 40 | ||
| Auburn 31 | L.S.U. (-5 1/2) 28 | ||
| September 21st: | Minnesota 32 | Green Bay (-12 1/2) 38 | |
| Kansas City 35 | Carolina (-5 1/2) 14 | ||
| Oakland 22 | New York Jets (-1 1/2) 23 | ||
| Cincinnati 20 | Denver (-12 1/2) 38 | ||
| Miami 21 | Tampa Bay (-3 1/2) 31 | ||
| September 22nd: | Pittsburgh 21 | Jacksonville (-3 1/2) 30 |