| Date | Visitor | Home | |
|---|---|---|---|
| September 13th: | Colorado 3 | Michigan (-1 1/2) 27 | |
| West Virginia (-6 1/2) 24 | Boston College 31 | ||
| Missouri 7 | Kansas (-2 1/2) 15 | ||
| Tulsa 16 | Iowa (-25 1/2) 54 | ||
| Notre Dame (-19 1/2) 17 | Purdue 28 | ||
| Illinois 14 | Louisville (-6 1/2) 26 | ||
| Arizona State 23 | Miami(Fla) (-9 1/2) 12 | ||
| Syracuse 3 | Virginia Tech (-3 1/2) 31 | ||
| Iowa State 29 | Minnesota (-9 1/2) 53 | ||
| September 14th: | Miami 18 | Green Bay (-12 1/2) 23 | |
| Detroit 32 | Chicago (-2 1/2) 7 | ||
| Tampa Bay 28 | Minnesota (-4 1/2) 14 | ||
| St. Louis 14 | Denver (-13 1/2) 35 | ||
| New York Jets 24 | New England (-9 1/2) 27 (ot) | ||
| September 15th: | Philadelphia 20 | Dallas (-9 1/2) 21 |