| Oct 19: | Indiana 20 | at Michigan (-23 1/2) 27 |
| Colorado (-8) 20 | at Kansas 7 | |
| Northwestern 34 | at Wisconsin (-3 1/2) 30 | |
| Iowa 21 | at Penn State (-10) 20 | |
| Iowa State 27 | at Oklahoma State (pk) 28 | |
| Southern Cal 35 | at Arizona State (-7) 48 | |
| Nebraska (-23 1/2) 24 | at Texas Tech 10 | |
| Auburn 10 | at Florida (-22 1/2) 44 | |
| U.C.L.A. 21 | at Washington (-6 1/2) 41 | |
| Kansas State 23 | at Texas A&M (pk) 20 | |
| East Carolina 31 | at Miami(Fla) (-17 1/2) 6 | |
| Oct 20: | Miami 28 | at Philadelphia (-3) 35 |
| New England 27 | at Indianapolis (-3 1/2) 9 | |
| Pittsburgh (-2) 13 | at Houston 23 | |
| Oct 21: | Oakland 23 | at San Diego (-3 1/2) 14 |