| Sept 21: | Notre Dame(-3 1/2) 27 | at Texas 24 |
| Northern Iowa 23 | at Iowa State(-3) 42 | |
| Florida 35 | at Tennessee(-3) 29 | |
| Arizona 17 | at Washington(-5 1/2) 31 | |
| Texas Tech(-1) 12 | at Georgia 15 | |
| Clemson(-7) 24 | at Missouri 38 | |
| Iowa(-17 1/2) 20 | at Tulsa 27 | |
| L.S.U. 19 | at Auburn(-7) 15 | |
| Nebraska(-23 1/2) 0 | at Arizona State 19 | |
| Sept 22: | Denver 14 | at Kansas City(-5) 17 |
| Green Bay(-6 1/2) 21 | at Minnesota 30 | |
| Dallas(-3) 7 | at Buffalo 10 | |
| Chicago 16 | at Detroit(-4 1/2) 35 | |
| Philadelphia 33 | at Atlanta(-1 1/2) 18 | |
| Sept 23: | Miami 6 | at Indianapolis(-2 1/2) 10 |