| San Diego(-4 1/2) 27 | at New York Giants 17 |
| Detroit(-7 1/2) 37 | at Tampa Bay 10 |
| New England 7 | at Indianapolis(-6) 10 |
| San Francisco(-10) 27 | at Atlanta 28 |
| Pittsburgh 19 | at Green Bay(-3 1/2) 24 |
| Seattle 3 | at Kansas City(-7) 26 |
| Philadelphia 14 | at Chicago(-3) 20 |
| Minnesota(-5 1/2) 24 | at Cincinnati 27 |
| Houston 28 | at Buffalo(-4 1/2) 17 |
| Miami(-6 1/2) 41 | at St. Louis 22 |
| Denver 31 | at Oakland(-5 1/2) 28 |
| Dallas(-9) 37 | at Arizona 13 |