History of Clemson Tigers
Versus South Carolina Gamecocks
| 11/26/11 | 13 | 34 | | Lost | | | @ Columbia, SC |
| 11/24/12 | 27 | 17 | | Lost | | | @ Clemson, SC |
| 11/30/13 | 17 | 31 | | Lost | | | @ Columbia, SC |
| 11/29/14 | 17 | 35 | | Won | | | @ Clemson, SC |
| 11/28/15 | 37 | 32 | | Won | | | @ Columbia, SC |
| 11/26/16 | 7 | 56 | | Won | -27 W | 49.5 O | @ Clemson, SC |
| 11/25/17 | 34 | 10 | | Won | -13 W | 46.5 U | @ Columbia, SC |
| 11/24/18 | 35 | 56 | | Won | -26 L | 58.5 O | @ Clemson, SC |
| 11/30/19 | 38 | 3 | | Won | -27.5 W | 50.5 U | @ Columbia, SC |
| 11/27/21 | 30 | 0 | | Won | -11.5 W | 43 U | @ Columbia, SC |
| 11/26/22 | 31 | 30 | | Lost | -14.5 L | 53.5 O | @ Clemson, SC |
| 11/25/23 | 16 | 7 | | Won | -7.5 W | 48.5 U | @ Columbia, SC |
| 11/30/24 | 17 | 14 | | Lost | -3 L | 49.5 U | @ Clemson, SC |
| totals | | 8-5 | (5-3) | |