History of Iowa State Cyclones
Versus Texas Tech Red Raiders
| 10/29/11 | 41 | 7 | | Won | | | @ Lubbock, TX |
| 09/29/12 | 24 | 13 | | Lost | | | @ Ames, IA |
| 10/12/13 | 35 | 42 | | Lost | | | @ Lubbock, TX |
| 11/22/14 | 34 | 31 | | Lost | | | @ Ames, IA |
| 10/10/15 | 31 | 66 | | Lost | | | @ Lubbock, TX |
| 11/19/16 | 10 | 66 | | Won | +3.5 W | 76.5 U | @ Ames, IA |
| 10/21/17 | 31 | 13 | | Won | +6.5 W | 67.5 U | @ Lubbock, TX |
| 10/27/18 | 31 | 40 | | Won | -5.5 W | 58 O | @ Ames, IA |
| 10/19/19 | 34 | 24 | | Won | -8.5 W | 58 T | @ Lubbock, TX |
| 10/10/20 | 15 | 31 | | Won | -10 W | 63.5 U | @ Ames, IA |
| 11/13/21 | 38 | 41 | | Lost | -12 L | 56 O | @ Lubbock, TX |
| 11/19/22 | 14 | 10 | | Lost | -3.5 L | 47.5 U | @ Ames, IA |
| 11/02/24 | 23 | 22 | | Lost | -13.5 L | 55.5 U | @ Ames, IA |
| totals | | 6-7 | (5-3) | |