History of Penn State Nittany Lions
Versus Ohio State Buckeyes
| 11/19/11 | 20 | 14 | | Won | | | @ Columbus, OH |
| 10/27/12 | 35 | 23 | | Lost | | | @ University Park, PA |
| 10/26/13 | 14 | 63 | | Lost | | | @ Columbus, OH |
| 10/25/14 | 31 | 24 | (ot) | Lost | | | @ University Park, PA |
| 10/17/15 | 10 | 38 | | Lost | | | @ Columbus, OH |
| 10/22/16 | 21 | 24 | | Won | +17.5 W | 55.5 U | @ University Park, PA |
| 10/28/17 | 38 | 39 | | Lost | +7 W | 57.5 O | @ Columbus, OH |
| 09/29/18 | 27 | 26 | | Lost | +3.5 W | 69.5 U | @ University Park, PA |
| 11/23/19 | 17 | 28 | | Lost | +20.5 W | 58 U | @ Columbus, OH |
| 10/31/20 | 38 | 25 | | Lost | +10 L | 63 T | @ University Park, PA |
| 10/30/21 | 24 | 33 | | Lost | +19.5 W | 60.5 U | @ Columbus, OH |
| 10/29/22 | 44 | 31 | | Lost | +15.5 W | 60.5 O | @ University Park, PA |
| 10/21/23 | 12 | 20 | | Lost | +4 L | 46.5 U | @ Columbus, OH |
| 11/02/24 | 20 | 13 | | Lost | +3.5 L | 47.5 U | @ University Park, PA |
| totals | | 2-12 | (6-3) | |