History of Houston Texans
Versus Tennessee Titans
| 10/23/11 | 41 | 7 | | Won | | | @ Nashville, TN |
| 01/01/12 | 23 | 22 | | Lost | | | @ Houston, TX |
| 09/30/12 | 14 | 38 | | Won | | | @ Houston, TX |
| 12/02/12 | 24 | 10 | | Won | | | @ Nashville, TN |
| 09/15/13 | 24 | 30 | (ot) | Won | | | @ Houston, TX |
| 12/29/13 | 10 | 16 | | Lost | | | @ Nashville, TN |
| 10/26/14 | 30 | 16 | | Won | | | @ Nashville, TN |
| 11/30/14 | 21 | 45 | | Won | | | @ Houston, TX |
| 11/01/15 | 6 | 20 | | Won | | | @ Houston, TX |
| 12/27/15 | 34 | 6 | | Won | | | @ Nashville, TN |
| 10/02/16 | 20 | 27 | | Won | -4 W | 40 O | @ Houston, TX |
| 01/01/17 | 17 | 24 | | Lost | +3 L | 41 T | @ Nashville, TN |
| 10/01/17 | 14 | 57 | | Won | +2.5 W | 43 O | @ Houston, TX |
| 12/03/17 | 13 | 24 | | Lost | +7 L | 42.5 U | @ Nashville, TN |
| 09/16/18 | 17 | 20 | | Lost | -3.5 L | 41 U | @ Nashville, TN |
| 11/26/18 | 17 | 34 | | Won | -3.5 W | 42.5 O | @ Houston, TX |
| 12/15/19 | 24 | 21 | | Won | +3 W | 50.5 U | @ Nashville, TN |
| 12/29/19 | 35 | 14 | | Lost | +9.5 L | 43 O | @ Houston, TX |
| 10/18/20 | 36 | 42 | (ot) | Lost | +4 L | 52 O | @ Nashville, TN |
| 01/03/21 | 41 | 38 | | Lost | +7 W | 55.5 O | @ Houston, TX |
| 11/21/21 | 22 | 13 | | Won | +10 W | 45 U | @ Nashville, TN |
| 01/09/22 | 28 | 25 | | Lost | +11 W | 43 O | @ Houston, TX |
| 10/30/22 | 17 | 10 | | Lost | +1.5 L | 39.5 U | @ Houston, TX |
| 12/24/22 | 19 | 14 | | Won | +3.5 W | 34.5 U | @ Nashville, TN |
| 12/17/23 | 19 | 16 | (ot) | Won | +3.5 W | 38.5 U | @ Nashville, TN |
| 12/31/23 | 3 | 26 | | Won | -5.5 W | 43.5 U | @ Houston, TX |
| totals | | 16-10 | (10-6) | |