History of Michigan State Spartans
Versus Penn State Nittany Lions
| 11/29/14 | 34 | 10 | | Won | | | @ University Park, PA |
| 11/28/15 | 16 | 55 | | Won | | | @ East Lansing, MI |
| 11/26/16 | 12 | 45 | | Lost | +11.5 L | 53.5 O | @ University Park, PA |
| 11/04/17 | 24 | 27 | | Won | +10 W | 46.5 O | @ East Lansing, MI |
| 10/13/18 | 21 | 17 | | Won | +13.5 W | 54 U | @ University Park, PA |
| 10/26/19 | 28 | 7 | | Lost | +5.5 L | 42 U | @ East Lansing, MI |
| 12/12/20 | 24 | 39 | | Lost | +15 T | 46.5 O | @ University Park, PA |
| 11/27/21 | 27 | 30 | | Won | +4 W | 51.5 O | @ East Lansing, MI |
| 11/26/22 | 16 | 35 | | Lost | +19.5 W | 53.5 U | @ University Park, PA |
| 11/24/23 | 42 | 0 | | Lost | +22.5 L | 43.5 U | @ East Lansing, MI |
| totals | | 5-5 | (4-3-1) | |