History of New York Jets
Versus Buffalo Bills
| 11/06/11 | 27 | 11 | | Won | | | @ Orchard Park, NY |
| 11/27/11 | 24 | 28 | | Won | | | @ East Rutherford, NJ |
| 09/09/12 | 28 | 48 | | Won | | | @ East Rutherford, NJ |
| 12/30/12 | 9 | 28 | | Lost | | | @ Orchard Park, NY |
| 09/22/13 | 20 | 27 | | Won | | | @ East Rutherford, NJ |
| 11/17/13 | 14 | 37 | | Lost | | | @ Orchard Park, NY |
| 10/26/14 | 43 | 23 | | Lost | | | @ East Rutherford, NJ |
| 11/24/14 | 3 | 38 | | Lost | | | @ Detroit, MI |
| 11/12/15 | 22 | 17 | | Lost | | | @ East Rutherford, NJ |
| 01/03/16 | 17 | 22 | | Lost | | | @ Orchard Park, NY |
| 09/15/16 | 37 | 31 | | Won | pk W | 40.5 O | @ Orchard Park, NY |
| 01/01/17 | 10 | 30 | | Won | +4 W | 43 U | @ East Rutherford, NJ |
| 09/10/17 | 12 | 21 | | Lost | +7.5 L | 42 U | @ Orchard Park, NY |
| 11/02/17 | 21 | 34 | | Won | +3.5 W | 42.5 O | @ East Rutherford, NJ |
| 11/11/18 | 41 | 10 | | Lost | -7 L | 37.5 O | @ East Rutherford, NJ |
| 12/09/18 | 27 | 23 | | Won | +4.5 W | 37 O | @ Orchard Park, NY |
| 09/08/19 | 17 | 16 | | Lost | -3 L | 41.5 U | @ East Rutherford, NJ |
| 12/29/19 | 13 | 6 | | Won | -1 W | 37 U | @ Orchard Park, NY |
| 09/13/20 | 17 | 27 | | Lost | +6 L | 39 O | @ Orchard Park, NY |
| 10/25/20 | 18 | 10 | | Lost | +10 W | 46.5 U | @ East Rutherford, NJ |
| 11/14/21 | 45 | 17 | | Lost | +13 L | 48.5 O | @ East Rutherford, NJ |
| 01/09/22 | 10 | 27 | | Lost | +15.5 L | 42.5 U | @ Orchard Park, NY |
| 11/06/22 | 17 | 20 | | Won | +10.5 W | 45.5 U | @ East Rutherford, NJ |
| 12/11/22 | 12 | 20 | | Lost | +9.5 W | 43.5 U | @ Orchard Park, NY |
| 09/11/23 | 16 | 22 | (ot) | Won | +2.5 W | 44.5 U | @ East Rutherford, NJ |
| 11/19/23 | 6 | 32 | | Lost | +8 L | 39.5 U | @ Orchard Park, NY |
| 10/14/24 | 23 | 20 | | Lost | +1.5 L | 41 O | @ East Rutherford, NJ |
| totals | | 11-16 | (9-8) | |