History of San Francisco 49ers
Versus Green Bay Packers
| 09/09/12 | 30 | 22 | | Won | | | @ Green Bay, WI |
| 01/12/13 | 31 | 45 | | Won | | | @ San Francisco, CA |
| 09/08/13 | 28 | 34 | | Won | | | @ San Francisco, CA |
| 01/05/14 | 23 | 20 | | Won | | | @ Green Bay, WI |
| 10/04/15 | 17 | 3 | | Lost | | | @ San Francisco, CA |
| 10/15/18 | 30 | 33 | | Lost | +9.5 W | 46.5 O | @ Green Bay, WI |
| 11/24/19 | 8 | 37 | | Won | -3 W | 48 U | @ San Francisco, CA |
| 01/19/20 | 20 | 37 | | Won | -8 W | 47 O | @ San Francisco, CA |
| 11/05/20 | 34 | 17 | | Lost | +6 L | 48.5 O | @ San Francisco, CA |
| 09/26/21 | 30 | 28 | | Lost | -3 L | 51 O | @ San Francisco, CA |
| 01/22/22 | 13 | 10 | | Won | +6 W | 47.5 U | @ Green Bay, WI |
| 01/20/24 | 21 | 24 | | Won | -10.5 L | 50.5 U | @ San Francisco, CA |
| 11/24/24 | 10 | 38 | | Lost | +6.5 L | 44.5 O | @ Green Bay, WI |
| totals | | 8-5 | (4-4) | |