History of Iowa State Cyclones
Versus Kansas Jayhawks
| 11/05/11 | 10 | 13 | | Won | | | @ Ames, IA |
| 11/17/12 | 51 | 23 | | Won | | | @ Lawrence, KS |
| 11/23/13 | 0 | 34 | | Won | | | @ Ames, IA |
| 11/08/14 | 14 | 34 | | Lost | | | @ Lawrence, KS |
| 10/03/15 | 13 | 38 | | Won | | | @ Ames, IA |
| 11/12/16 | 31 | 24 | | Won | -10.5 L | 55 T | @ Lawrence, KS |
| 10/14/17 | 0 | 45 | | Won | -22.5 W | 62 U | @ Ames, IA |
| 11/03/18 | 27 | 3 | | Won | -18 W | 47 U | @ Lawrence, KS |
| 11/23/19 | 31 | 41 | | Won | -26 L | 58 O | @ Ames, IA |
| 10/31/20 | 52 | 22 | | Won | -27 W | 49.5 O | @ Lawrence, KS |
| 10/02/21 | 7 | 59 | | Won | -34.5 W | 57 O | @ Ames, IA |
| 10/01/22 | 11 | 14 | | Lost | -3.5 L | 58.5 U | @ Lawrence, KS |
| 11/04/23 | 28 | 21 | | Lost | -2.5 L | 53.5 U | @ Ames, IA |
| 11/09/24 | 36 | 45 | | Lost | -2.5 L | 52.5 O | @ Kansas City, MO |
| totals | | 10-4 | (4-5) | |