History of Louisville Cardinals
Versus Boston College Eagles
| 11/08/14 | 38 | 19 | | Won | | | @ Chestnut Hill, MA |
| 10/24/15 | 14 | 17 | | Won | | | @ Louisville, KY |
| 11/05/16 | 52 | 7 | | Won | -25 W | 52 O | @ Chestnut Hill, MA |
| 10/14/17 | 45 | 42 | | Lost | -19 L | 60 O | @ Louisville, KY |
| 10/13/18 | 20 | 38 | | Lost | +12 L | 57 O | @ Chestnut Hill, MA |
| 10/05/19 | 39 | 41 | | Won | -4 L | 61 O | @ Louisville, KY |
| 11/28/20 | 27 | 34 | | Lost | +1 L | 56.5 O | @ Chestnut Hill, MA |
| 10/23/21 | 14 | 28 | | Won | -4 W | 57.5 U | @ Louisville, KY |
| 10/01/22 | 33 | 34 | | Lost | -13.5 L | 49 O | @ Chestnut Hill, MA |
| 09/23/23 | 28 | 56 | | Won | -14 W | 53 O | @ Louisville, KY |
| 10/25/24 | 31 | 27 | | Won | -7 L | 54 O | @ Chestnut Hill, MA |
| totals | | 7-4 | (3-6) | |