| Wednesday, Dec 25 | 12:00 PM | Kansas City at Pittsburgh |
| Pittsburgh by 0.86 | ||
| 3:30 PM | Baltimore at Houston | |
| Baltimore by 5.01 | ||
| Thursday, Dec 26 | 7:15 PM | Seattle at Chicago |
| Seattle by 2.96 | ||
| Saturday, Dec 28 | 12:00 PM | L.A. Chargers at New England |
| L.A. Chargers by 5.08 | ||
| 3:30 PM | Denver at Cincinnati | |
| Cincinnati by 2.17 | ||
| 7:00 PM | Arizona at L.A. Rams | |
| L.A. Rams by 7.74 | ||
| Sunday, Dec 29 | 12:00 PM | N.Y. Jets at Buffalo |
| Buffalo by 13.51 | ||
| 12:00 PM | Green Bay at Minnesota | |
| Green Bay by 3.22 | ||
| 12:00 PM | Las Vegas at New Orleans | |
| New Orleans by 3.53 | ||
| 12:00 PM | Carolina at Tampa Bay | |
| Tampa Bay by 12.84 | ||
| 12:00 PM | Tennessee at Jacksonville | |
| Jacksonville by 3.85 | ||
| 12:00 PM | Indianapolis at N.Y. Giants | |
| Indianapolis by 6.24 | ||
| 3:05 PM | Miami at Cleveland | |
| Miami by 2.98 | ||
| 3:25 PM | Dallas at Philadelphia | |
| Philadelphia by 11.37 | ||
| 7:20 PM | Atlanta at Washington | |
| Washington by 6.71 | ||
| Monday, Dec 30 | 7:15 PM | Detroit at San Francisco |
| Detroit by 10.45 | ||